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发布时间: 2024年12月18日 21:18
霍然,博士,女,1978年1月出生,现任南京医科大学组织胚胎学系副教授,硕士生导师。2002年毕业于东南大学与 南京医科大学联合培养生物医学工程及临床医学双学位专业;2006年毕业于南京医科大学人体解剖与组织胚胎学系,获博士学位。近年来主要从事配子发生、成 熟及早期胚胎发育相关的蛋白质组学及蛋白功能研究。主持完成了国家973计划课题及国家自然科学基金青年科学基金项目各一项,在本领域专业期刊上发表 SCI论文20余篇。
社会兼职:
中科院动物所兼职副研究员,中国解剖学会会员
获奖:
2010年 精子发生相关蛋白质组学研究获教育部2010年度高等学校科学研究优秀成果奖(自然科学奖)二等奖 (排名第三)
2009年被却确立为江苏省第三期333工程第3层次培养对象
代表性论文:
Guo X,Zhao C,Wang F,Zhu Y,Cui Y,Zhou Z,Huo R,Sha J. Investigation of human testis protein heterogeneity using 2-dimensional electrophoresis. J Androl. 2010 Jul-Aug;31(4):419-29. corresponding author
Ma M,Zhou L,Guo X,Lv Z,Yu Y,Ding C,Zhang P,Bi Y,Xie J,Wang L,Lin M,Zhou Z,Huo R#,Sha J,Zhou Q#,. Decreased cofilin1 expression is important for compaction during early mouse embryo development. Biochim Biophys Acta. 2009 Dec;1793(12):1804-10. #co-corresponding author
Zhang P,Ni X,Guo Y,Guo X,Wang Y,Zhou Z,Huo R,Sha J. Proteomic-based identification of maternal proteins in mature mouse oocytes. BMC Genomics. 2009 Aug 3;10:348. corresponding author
Yu Y,Wu JD,Fan Y,Lv Z,Guo XJ,Zhao C,Zhou R,Zhang Z,Wang FQ,Xiao M,Chen L,Zhu H,Chan W,Lin M,Liu JY,Zhou ZM,Wang L,Huo R#,Zhou Q#,Sha JH. evaluation of blastomere biopsy using mouse model indicates the potential high-risk of neurodegenerative disorders in the offspring. Mol Cell Proteomics. 2009 Jul;8(7):1490-500.. #co-corresponding author
Ma M,Guo X,Wang F,Zhao C,Liu Z,Shi Z,Wang Y,Zhang P,Zhang K,Wang N,Lin M,Zhou Z,Liu J,Li Q,Wang L,Huo R#,Sha J,Zhou Q#. Protein expression profile of the mouse metaphase-II oocyte. J Proteome Res. 2008 Nov;7(11):4821-30. #co-corresponding author
Huo R,He Y,Zhao C,Guo XJ,Lin M,Sha JH. Identification of human spermatogenesis-related proteins by comparative proteomic analysis: a preliminary study. Fertil Steril. 2008 Oct;90(4):1109-18.
Zhao C*,Huo R*,Wang FQ,Lin M,Zhou ZM,Sha JH. Identification of several proteins involved in regulation of sperm motility by proteomic analysis. Fertil Steril. 2007 Feb;87(2):436-8. *co-author
Lu Y*,Huo R*,Yuan Y,Li J,Shi Q,Sha J. Human testicular protein NYD-SP16 is involved in sperm capacitation and the acrosome reaction. Fertil Steril. 2006 Oct;86(4 Suppl):1228-34. *co-author
Huo R,Zhu H,Lu L,Ying L,Xu M,Xu Z,Li J,Zhou Z,Sha J. Molecular cloning,identification and characteristics of a novel isoform of carbamyl phosphate synthetase I in human testis. J Biochem Mol Biol. 2005 Jan 31;38(1):28-33.
Huo R*,Zhu YF*,Ma X,Lin M,Zhou ZM,Sha JH. Differential expression of glucose-regulated protein 78 during spermatogenesis. Cell Tissue Res. 2004 Jun;316(3):359-67. *co-author
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